The NI PCI-6251 is a 16-bit multifunction DAQ module for PCI bus systems, delivering integrated analog and digital I/O with counter/timer capabilities. It combines 16 analog input channels, 2 analog output channels, 24 digital I/O lines, and two 32-bit counters/timers—all controlled through NI-DAQmx driver software. The M Series architecture incorporates NI-MCal calibration technology and the NI-STC 2 system controller to optimize measurement accuracy at high sampling rates, making it suitable for laboratory automation, automated testing, design verification, and manufacturing test environments.
Technical Specifications
Analog Inputs
• 16 channels, 16-bit resolution
• 1.25 MS/s per channel (single-channel maximum); 1.00 MS/s multichannel aggregate rate
• Programmable input ranges: ±10 V, ±5 V, ±2.0 V, ±1.0 V, ±0.5 V, ±0.2 V, ±0.1 V
• Referenced Single-Ended, Non-Referenced Single-Ended, and Differential input configurations (8 differential or 16 single-ended)
• High CMRR: 100 dB; crosstalk: −95 dB (non-adjacent), −75 dB (adjacent channels)
• Onboard NI-PGIA 2 amplifier for fast settling at high scanning rates
Analog Outputs
• 2 channels, 16-bit resolution
• 2.8 MS/s update rate (single-channel); 2.00 MS/s (two-channel maximum)
• Selectable output ranges: ±10 V, ±5 V
• DNL correction and overdrive protection
Digital I/O
• 24 programmable TTL/CMOS lines (individually configurable as input or output)
• 8 clocked lines for correlated DIO
Counters/Timers
• Two 32-bit counters/timers
• 80 MHz timebase clock rate
– Key Features
• Fast settling NI-PGIA 2 amplifier ensures 16-bit accuracy without compromising scan speed
• Per-channel range selection optimizes signal conditioning across diverse measurement types
• Correlated digital I/O synchronizes with analog and counter operations
• NI-MCal internal calibration maintains absolute accuracy within 10 °C of external calibration
– Typical Applications
Laboratory automation, automated test systems, design verification, manufacturing test, research instrumentation.
– Compatibility & Integration
NI-DAQmx driver software provides configuration, signal routing, and measurement execution across all integrated I/O functions.

















