The Keysight U2653A is a USB modular digital I/O device that delivers 64 opto-isolated output channels for data acquisition, industrial automation, and automated testing applications. Built on a high-speed USB 2.0 interface with USBTMC-USB488 compliance, the unit provides 1250 Vrms isolation protection and supports output voltages to 35 V. It operates as a standalone instrument or integrates into larger modular measurement systems, enabling flexible deployment across diverse test environments.
Technical Specifications
• 64 digital output lines with opto-isolation
• Maximum output voltage: 35 V
• Isolation rating: 1250 Vrms
• Interface: USB 2.0 (high-speed), USBTMC-USB488 compliant
• Operating system: Microsoft® Windows®
– Key Features
• Opto-isolated output channels for signal integrity and galvanic separation
• Interrupt support for event-driven operation
• Virtual port grouping for logical channel management
• Standalone or modular configuration options
• Compatible with optional U2903A or U2904A terminal blocks for field wiring
• Software integration with Keysight VEE, MATLAB® R2007a, NI LabVIEW, and Microsoft® Visual Studio®
• Includes Keysight BenchVue software license for instrument control and test automation
– Typical Applications
• Data acquisition systems
• Industrial automation and process control
• Automated test equipment (ATE)
• Signal routing and switching
• Digital state monitoring and output control
– Compatibility & Integration
The U2653A interfaces with Microsoft® Windows® environments and supports development in Keysight VEE, MATLAB® R2007a, NI LabVIEW, and Microsoft® Visual Studio®. Terminal connectivity is achieved through optional U2903A or U2904A blocks, enabling rapid integration into existing bench and production test setups.


















