The Keysight U2351A is a USB modular multifunction data acquisition device that combines analog input, analog output, digital I/O, and counter/timer functionality in a single compact unit. Designed for portable and benchtop measurement applications, it delivers 16-bit resolution across 16 single-ended or 8 differential analog input channels, with dual 16-bit analog outputs and 24 programmable digital I/O lines. The device operates via high-speed USB 2.0 connectivity and integrates directly with popular development platforms including LabVIEW, MATLAB, Visual Studio, and Keysight VEE.
Technical Specifications
Analog Input
• Resolution: 16-bit
• Channels: 16 single-ended or 8 differential multiplexed
• Sampling Rate: Up to 250 kSa/s
• Bandwidth: 400 kHz
• Maximum Input Voltage: 12 V
• Maximum Input Current: 10 µA
Analog Output
• Channels: 2
• Resolution: 16-bit
• Maximum Update Rate: 1 MSa/s
• Waveform Capability: Predefined or arbitrary waveforms
Digital I/O
• Channels: 24-bit programmable TTL input/output
• Applications: Closed-loop control via switches, relays, and solenoids
Counters/Timers
• Channels: 2 general purpose digital counter channels
Connectivity & Software
• Interface: USB 2.0 (USBTMC-USB488 standard)
• Operating Systems: Windows
• Development Environments: Keysight VEE, MATLAB R2007a, NI LabVIEW, Microsoft Visual Studio
• Bundled Software: Keysight BenchVue (BV0025B) and Measurement Manager
Physical & Environmental
• Dimensions: 182.4 mm × 120 mm × 44 mm
• Operating Temperature: 0 °C to 55 °C
– Key Features
• Burst mode for simulated simultaneous analog input acquisition
• Polling mode operation as a digital multimeter or basic oscilloscope with triggering
• Optional terminal block connectivity (U2901A or U2902A) for simplified wiring
• Modular integration with U2781A USB chassis for multi-instrument synchronization
– Typical Applications
• Design validation and prototype testing
• Manufacturing test and quality assurance
• Data logging and long-term monitoring
• Closed-loop measurement and control systems
– Compatibility & Integration
Standalone operation is supported, or the U2351A can integrate into a modular measurement system via the optional U2781A USB chassis. Synchronization and triggering capabilities enable flexible measurement setups across multiple instruments and channels.


















